Peptide lexicon
hCG (Choriongonadotropin)
Human chorionic gonadotropin, a glycoprotein hormone of α and β subunits acting at the LH receptor.
| Substance class | Peptide |
|---|---|
| Synonyms | Humanes Choriongonadotropin, hCG |
Structure
hCG consists of an α subunit (shared with LH, FSH and TSH) and a specific β subunit with a long glycosylated C-terminus. Amounts are given in international units (IU).
State of research
Research covers LH/hCG receptor activation, steroidogenesis in Leydig and granulosa cells and the role of hCG in early pregnancy.
Status
hCG is an approved prescription-only medicinal substance and is on the WADA Prohibited List for males. The material offered here is a research reagent.
Literature
- The association between human chorionic gonadotropin and adverse pregnancy outcomes: a systematic review and meta-analysisAm J Obstet Gynecol, 2024 · PMID 37572838 · DOI 10.1016/j.ajog.2023.08.007
- Human Chorionic Gonadotropin and Early Embryogenesis: ReviewInt J Mol Sci, 2022 · PMID 35163303 · DOI 10.3390/ijms23031380
- Human Chorionic Gonadotropin-A Review of the LiteratureObstet Gynecol Surv, 2022 · PMID 36136076 · DOI 10.1097/OGX.0000000000001053
- Human Chorionic Gonadotropin and Breast CancerInt J Mol Sci, 2017 · PMID 28754015 · DOI 10.3390/ijms18071587
- Immunoassay of human chorionic gonadotropin, its free subunits, and metabolitesClin Chem, 1997 · PMID 9439438
