What is Matrixyl?
Matrixyl consists of the pentapeptide Lys-Thr-Thr-Lys-Ser, a segment of type I procollagen, with palmitic acid on the N-terminus for better skin penetration.
More data in the lexicon entry on Matrixyl.
State of research
The idea behind Matrixyl comes from wound healing research: short collagen fragments act as a signal that tissue needs repair. The pentapeptide KTTKS stimulated collagen I and III and fibronectin production in fibroblasts; the palmitic acid is meant to improve skin penetration.
A controlled study of 93 women (Robinson et al., 2005) found measurably fewer fine lines after twelve weeks with a Matrixyl cream than with the vehicle alone. Larger independent studies are rare, and mechanisms in intact skin are not fully understood. Matrixyl is nonetheless a reference substance in anti-ageing peptide research.
Status and quality
Matrixyl is widely used as a cosmetic ingredient but is not approved as a medicine. Peptidkauf sells Matrixyl solely as a research reagent for laboratory and in-vitro use and gives no dosing or application advice.
An independent laboratory tests every batch for purity (HPLC), identity and measured content before it goes on sale; the reports and their verification keys are in the lab report archive. The material ships as lyophilised powder in a glass vial; storage and laboratory handling are covered under storage & handling.
Related products and articles
More skin peptides: SNAP-8, GHK-Cu, AHK-Cu. Overview in the skin and copper peptides research area.
