Peptide lexicon
Somatropin (HGH 191AA)
Recombinant human growth hormone of 191 amino acids (22 kDa), identical to the pituitary hormone.
| Substance class | Peptide |
|---|---|
| Synonyms | HGH 191AA, rhGH, rekombinantes humanes Wachstumshormon |
Structure
Somatropin is a single-chain protein of 191 amino acids with two disulfide bridges. It is produced recombinantly; the amount in international units (IU) refers to biological activity (1 mg ≈ 3 IU).
State of research
Research covers signalling through the growth hormone receptor (JAK2/STAT5), hepatic IGF-1 production and effects on bone, muscle and fat metabolism.
Status
Somatropin is an approved prescription-only medicinal substance and is on the WADA Prohibited List. The material offered here is a research reagent.
Literature
- Lonapegsomatropin2006 · PMID 34554672
- Somatropin2006 · PMID 30000556
- Disorders of Growth Hormone in Childhood2000 · PMID 25905205
- Somatrem2006 · PMID 30000557
- Somatrogon2006 · PMID 40864839
