Peptide lexicon
Vesugen
Tripeptide Lys-Glu-Asp from the group of short peptide bioregulators, studied in models of the vascular wall.
| Substance class | Peptide |
|---|---|
| Sequence | KED |
| CAS number | 204271-66-9 |
| Molecular formula | C₁₅H₂₆N₄O₈ |
| Molar mass | 390.39 g/mol |
| Synonyms | Lys-Glu-Asp |
| PubChem | CID 87571363 |
Structure
Vesugen is the tripeptide KED. It belongs to the synthetic short peptides of the St Petersburg Institute of Bioregulation and Gerontology.
Research focus
Publications describe effects on endothelial and vascular smooth muscle cells in culture, on markers of cellular ageing and binding models with DNA promoter regions.
Status
The literature comes mostly from one research group; independent replications are rare.
Literature
- Peptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in Alzheimer's DiseaseBull Exp Biol Med, 2021 · PMID 34173097 · DOI 10.1007/s10517-021-05192-6
- [Prospects for use of short peptides in pharmacotherapeutic correction of Alzheimer's disease.]Adv Gerontol, 2024 · PMID 38944767
- [The Role of Cytokines MIC-1/GDF15 in Development of the Old Age Disease]Usp Fiziol Nauk, 2015 · PMID 27183783
- [Adhesion molecule JAM-A, its function and mechanism of epigenetic regulation]Adv Gerontol, 2015 · PMID 28509452
- [EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION]Adv Gerontol, 2015 · PMID 26390612
